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Enzalutamide (CAS915087-33-1)

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English name

Enzalutamide恩杂鲁胺

Synonyms

4-{3-[4-cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-sulfanylideneiMidazolidin-1-yl}-2-fluoro-N-MethylbenzaMide;EnzalutaMide;MDV3100(EnzalutaMide);ENZALUTAMIDE;MDV-3100;MDV-3100;4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidChemicalbookinyl]-2-fluoro-N-methylbenzamide;4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide;MDV3100,4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-MethylbenzaMide

CAS

915087-33-1

EINECS

805-022-1

Molecular formula

C21H16F4N4O2S

Molecular weight

464.44

Chemical formula

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Content >


Density

1.49

Melting point

198 - 200°C

Solubility

Soluble in DMSO (>25 mg/ml)

Acidity coefficient

13.88±0.46(Predicted)

Storage condition

-20°C

Appearance

solid

Colour

White to off-white

Stability

Stable for 1 year as supplied. Solutions in DMSO may be stored at   -20°C for up to 3 months.

HS

29339900

Use

Enheterolumide can be used in almost all stages of prostate   cancer, such as advanced patients before chemotherapy, can significantly   delay the start of chemotherapy time in patients. In addition, it can   significantly improve the overall survival time and progression-free survival   time of patients with CRPC and mCRPC after chemotherapy.

Package

According to user requirements

Upstream raw materials

N - methyl - 4 - bromine - 2 - fluoro - 4 - the cyanide and   benzamide acyl - 2 - (three fluorinated methyl) cyanobenzene 4 - [(2 - cyano   - 2 - c) amino] - 2 - fluoro - N - methyl benzamide N - [Chemicalbook3 -   fluoro - 4 - [(methyl amino) carbonyl] phenyl] 2 - methyl - alanine methyl   1289942-5 5-7N-[3-fluoro-4 -[(methyl amino) carbonyl] phenyl]   -2-methylalanine