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Zolmitriptan (CAS139264-17-8)

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English name

Zolmitriptan 佐米曲普坦

Synonyms

(4r)-4-[[3-(2-dimethylaminoethyl)-1h-indol-5-yl]methyl]oxazolidin-2-one;Zolmitriptan;AssistsMiQuPuTanzania;Zolmitriptan(Chemicalbook150mg);(4R)-4-({3-[2-(diMethylaMino)ethyl]-1H-indol-5-yl}Methyl)-1,3-oxazolidin-2-one;ZolMitriptan(ZoMig);ZolMitriptanAPI

CAS

139264-17-8

EINECS

629-919-0

Molecular formula

C16H21N3O2

Molecular weight

287.36

Chemical formula

3ac7272623f82eca69628fd7b773b029_139264-17-8.gif                                                                                 

Content >


Density

1.217±0.06 g/cm3(Predicted)

Melting point

136-141°C

Specific rotation

D22 -5.79° (c = 0.5 in methanol)

Boiling point

563.3±38.0 °C(Predicted)

Solubility

Soluble in DMSO at 5mg/ml

Acidity coefficient

9.64(at 25)

λmax

225nm(lit.)

Storage condition

15-25°C

Appearance

powder

Colour

white to beige

optical activity

[α]/D -3 to -8°, c = 1 in methanol

Merck

14,10189

Stability

Stable for 2 years from date of purchase as supplied. Solutions in   DMSO may be stored at -20°C for up to 3 months.

InChIKey

ULSDMUVEXKOYBU-ZDUSSCGKSA-N

HS

29349990

Use

For the acute treatment of migraine with or without aura   symptoms.

Dangerous mark

Xi,Xn

Risk phrases

36/37/38-22

Safety phrases

26-36

WGK Germany

3

Hazard Note

women,TDLo,oral,6mg/kg/43W-I (6mg/kg),BEHAVIORAL:   HEADACHE,Lancet.  Vol. 353, Pg. 378,   1999.

RTECS

RQ2707000

Upstream raw materials

COPPER(II) OXIDE dimethylamine quinoline 6-dimethylaminopurine   methylsulfonate