English name | Mometasone Furoate糠酸莫米松 |
Synonyms | SCH-32088;MOMETASONE17-FUROATE;MOMETASONEFUROATE;NASONEX;(11-beta,16-alpha)-xy-16-methyl;pregna-1,4-diene-3,20-dione,9,21-dichloro-17-((2-furanylcarbonyl)oxy)-11-hydro;9-chloro-17-(2-chloroacetyl)-11,17-Chemicalbookdihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-onefuroate;(11BETA,16ALPHA)-9,21-DICHLORO-17-[(2-FURANYLCARBONYL)OXY]-11-HYDROXY-16-METHYLPREGNA-1,4-DIENE-3,20-DIONE |
CAS | 83919-23-7 |
EINECS | 617-501-0 |
Molecular formula | C27H30Cl2O6 |
Molecular weight | 521.43 |
Chemical formula |
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Content > | |
Density | 1.37±0.1 g/cm3(Predicted) |
Melting point | 218-220°C |
Specific rotation | D26 +58.3° (dioxane) |
optical activity | [α]/D +50 to +60°, c = 0.5 in methanol |
Boiling point | 655.5±55.0 °C(Predicted) |
Solubility | DMSO: ≥20mg/mL |
Acidity coefficient | 13.02±0.70(Predicted) |
Storage condition | 2-8°C |
Appearance | powder |
Colour | white to off-white |
InChIKey | WOFMFGQZHJDGCX-ZULDAHANSA-N |
HS | 29372290 |
Use | Local use of medium - effect corticosteroids, anti-inflammatory, antipruritic and constriction of blood vessels. It is used to relieve inflammation and itching in patients with skin diseases, especially in patients who respond to cortisone use |
Upstream raw materials | Anhydrous lithium furanyl chloride 4-dimethylaminopyridine 16alpha-hydroxyprednisolone methyl sulfonyl chloride 2, 3-dichloro-5, 6-dicyano-benzoquinone (DDQ) |