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Mometasone Furoate(CAS83919-23-7)

5b3081c62c8cdb8534b12f13652a1760_83919-23-7.gif

English name

Mometasone Furoate糠酸莫米松

Synonyms

SCH-32088;MOMETASONE17-FUROATE;MOMETASONEFUROATE;NASONEX;(11-beta,16-alpha)-xy-16-methyl;pregna-1,4-diene-3,20-dione,9,21-dichloro-17-((2-furanylcarbonyl)oxy)-11-hydro;9-chloro-17-(2-chloroacetyl)-11,17-Chemicalbookdihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-onefuroate;(11BETA,16ALPHA)-9,21-DICHLORO-17-[(2-FURANYLCARBONYL)OXY]-11-HYDROXY-16-METHYLPREGNA-1,4-DIENE-3,20-DIONE

CAS

83919-23-7

EINECS

617-501-0

Molecular formula

C27H30Cl2O6

Molecular weight

521.43

Chemical formula

5b3081c62c8cdb8534b12f13652a1760_83919-23-7.gif                                                                           

Content >


Density

1.37±0.1 g/cm3(Predicted)

Melting point

218-220°C

Specific rotation

D26 +58.3° (dioxane)

optical activity

[α]/D +50 to +60°, c = 0.5 in methanol

Boiling point

655.5±55.0 °C(Predicted)

Solubility

DMSO: ≥20mg/mL

Acidity coefficient

13.02±0.70(Predicted)

Storage condition

2-8°C

Appearance

powder

Colour

white to off-white

InChIKey

WOFMFGQZHJDGCX-ZULDAHANSA-N

HS

29372290

Use

Local use of medium - effect corticosteroids,   anti-inflammatory, antipruritic and constriction of blood vessels. It is used   to relieve inflammation and itching in patients with skin diseases,   especially in patients who respond to cortisone use

Upstream raw materials

Anhydrous lithium furanyl chloride 4-dimethylaminopyridine   16alpha-hydroxyprednisolone methyl sulfonyl chloride 2, 3-dichloro-5,   6-dicyano-benzoquinone (DDQ)