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Budesonide (CAS51333-22-3)

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English name

Budesonide 布地奈德

Synonyms

1,4-PREGNADIEN-(R,S)-11-BETA,16-ALPHA,17,21-TETROL-3,20-DIONECYCLIC16,17ACETAL;BIDIEN;BUDESONIDE;CORTIVENT;EChemicalbookNTOCORTCR;(11-beta,16-alpha)-16,17-(butylidenebis(oxy))-11,21-dihydroxypregna-1,4-dien;16-alpha)-et;PULMICORT

CAS

51333-22-3

EINECS

257-139-7

Molecular formula

C25H34O6

Molecular weight

430.53

Chemical formula

0b70143cf6558353e2d821bda20afba7_51333-22-3.gif                                                                                   

Density

1.1046 (rough estimate)

Melting point

221-232°C (dec.)

Specific rotation

D25 +98.9° (c = 0.28 in methylene chloride)

Boiling point

464.79°C (rough estimate)

Solubility

Practically insoluble in water, freely soluble in methylene   chloride, sparingly soluble in ethanol (96 per cent).

Solubility of water

21.53mg/L(temperature not stated)

Refractive index

1.4593 (estimate)

Acidity coefficient

12.87±0.10(Predicted)

Storage condition

Store at RT

Appearance

powder

Colour

White to Off-White

Merck

14,1468

BCS class

2

InChIKey

VOVIALXJUBGFJZ-KWVAZRHASA-N

HS

29372900

Use

For the treatment of skin diseases, asthma and other diseases

Dangerous mark

toxic substance Xn

Risk phrases

40-36/37/38-20/21/22

Safety phrases

22-36-26

WGK Germany

3

Hazard Note

LD50 oral in rat: > 3200mg/kg

RTECS

TU3723000

Hazard Class

toxicosis

Upstream raw materials

N-butyl hydrofluorate