English name | Escitalopram Oxalate 草酸艾司西酞普兰 |
Synonyms | (S)-CITALOPRAM;1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran-carbonitrileoxalate;ESCITALOPRAMOXALATE;S-(+)-CITAPROLAMOXALATE;S-(+)-1-3-(dimethyl-amino)proChemicalbookpyl-1-(p-fluorophenyl)-5-phthalancarbonitrileoxalate;ESCIFALOPRAMOXALATE;(S)-Citalopram-d6;1S)-1-[3-(Dimethylamino-d6)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile |
CAS | 219861-08-2 |
EINECS | 620-544-8 |
Molecular formula | C22H23FN2O5 |
Molecular weight | 414.43 |
Chemical formula |
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Melting point | 152-153°C |
Specific rotation | D +12.31° (c = 1 in methanol) |
Solubility | DMSO: ≥15mg/mL |
Storage condition | 2-8°C |
Appearance | powder |
Colour | white to tan |
PH | |
Merck | 14,2318 |
BCS class | 1 |
Stability | Hygroscopic |
InChI | InChI=1S/C20H21FN2O.C2H2O4/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;3-1(4)2(5)6/h4-9,12H,3,10-11,14H2,1-2H3;(H,3,4)(H,5,6) |
InChIKey | KTGRHKOEFSJQNS-UHFFFAOYSA-N |
HS | 29322090 |
SMILES | C1(CCCN(C)C)(C2=CC=C(F)C=C2)C2=C(C=C(C#N)C=C2)CO1.C(O)(=O)C(O)=O |
Use | D-citalopram, the active isomer of Citalopram (S-Citalopram), has a highly selective inhibitory effect on the reabsorption of 5-hydroxytryptamine (5-HT) with little effect on the reabsorption of norepinephrine and polychemicalbook pamine. It increases the concentration of 5-HT in the synaptic cleft by preventing 5-HT reabsorption, resulting in an antidepressant effect. It is mainly suitable for the treatment of severe depression. |
Package | （According to user requirements） |
Dangerous mark | Xi |
Risk phrases | 36/37/38 |
Safety phrases | 26-36 |
WGK Germany | 3 |
RTECS | NP6333500 |
Upstream raw materials | (-) 4 [4 - (dimethylamino) 1 - (4 - fluorinated phenyl) - 1 - (hydroxy butyl) - 3 - (hydroxy methyl) benzonitrile. Hydrobromide (right phthalein alvin intermediates) in his PuLun oxalic acid |
