English name | Dexmedetomidine hydrochloride 盐酸右美托咪定 |
Synonyms | 4-[(1r)-1-(2,3-dimethylphenyl)ethyl]-3h-imidazolehydrochloride;4-((s)-alpha,2,3-trimethylbenzyl)imidazolemonohydrochloride;DEXMEDETOMIDINEHCL;DEXMEDETOMIDINEHYDROCHLChemicalbookORIDE;DEMEDETOMIDINEHCL;Dexmedetomidine(Pilot);4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazolehydrochloride;4-((S)-α,2,3-Trimethylbenzyl)imidazolemonohydrochloride |
CAS | 145108-58-3 |
EINECS | 682-047-2 |
Molecular formula | C13H17ClN2 |
Molecular weight | 236.74 |
Density | 1.17 g/cm3 |
Melting point | 156.5-157.5° |
Specific rotation | +52.4° (c = 1 in water) |
optical activity | [α]/D +48 to +58°, c = 1 in H2O |
Solubility of water | H2O: soluble20mg/mL, clear |
Storage condition | 2-8°C |
Appearance | powder |
Colour | white to beige |
Merck | 14,2946 |
InChIKey | VPNGEIHDPSLNMU-MERQFXBCSA-N |
HS | 2933290000 |
Use | Dexmedetomidine hydrochloride is used for pain relief and sedation to facilitate surgery and mechanical ventilation. It has a high incidence of bradycardia and excessive sedation, which affects its wide use. |
Dangerous mark | Xn |
Risk phrases | 22-36/37/38 |
Safety phrases | 26-36/37/39 |
WGK Germany | 3 |
RTECS | NI5156750 |
