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DL-Dithiothreitol (CAS3483-12-3)


English name

DL-Dithiothreitol 二硫苏糖醇

Synonyms

DL-1,4-Dithiothreitol,1Msolutioninwater,formolecularbiology;Dithiothreitol,98%;DL-1,4-Dithiothreitol,DTT;DTTDL-1,4-Dithiothreitol;DL-Dithiothreitol,99%[forMolecularbiology];DL-1,Chemicalbook4-Dithiothreitol,DNAse,RNAseandProteasefree,forMolecularb;DL-1,4-Dithiothreitol,DNAse,RNAseandProteasefree,forMolecularbiology,99+%1GR;DL-1,4-Dithiothreitol,forbiocheMistry,99%1GR

CAS

3483-12-3

EINECS

222-468-7

Molecular formula

微信图片_20230425154537.png

Molecular weight

154.25

Chemical formula

C4H10O2S2

Content >

≥99.0%

Density

1.04 g/mL at 20 °C

Melting point

41-44 °C(lit.)

Specific rotation

-0.2~+0.2°(20℃/D)(c=5,H2O)

Boiling point

125 °C

Flashing point

>230 °F

Solubility

H2O: 50 mg/mL, clear, colorless

Solubility of water

freely soluble

Sensibility

Air Sensitive

Refractive index

1.5200 (estimate)

Acidity coefficient

pK1:8.9 (25°C)

λmax

λ: 260 nm Amax: 0.400λ: 280 nm Amax: 0.100

Storage condition

-20°C (or 4°C short term).

Appearance

Powder

Colour

White

PH

4.0-6.0 (20-25℃,    0.1m in H2O)

Acid-base indicator color-changing ph range

Unpleasant Odor

Merck

14,3376

BRN

1719757

Stability

Stability Stable, but heat sensitive. Incompatible with strong    oxidizing agents. Keep frozen at -20 to -10 C.

Odor

Unpleasant Odor

MDL

 

InChI

 

InChIKey

VHJLVAABSRFDPM-UHFFFAOYSA-N

Vapour pressure

0.019-0.29Pa at 20-50℃

LogP

0.07 at 25℃ and    pH5

HS

29309099

Use

Dithiothreitol (DTT) is a small molecule organic reducing    agent with chemical formula C4H10O2S2, which is mainly used in the field of biotechnology    as a protein cleavage reagent. At present, the synthesis method of    dithiothreitol, which is the most widely used in Chemicalbook, takes thritol    as the raw material, first oxidize it with potassium manganese, then obtain    thioglycolate intermediate under the action of thioacetic acid, and finally    hydrolyze the thioglycolate intermediate to obtain dithiothreitol.

Package

(According to user requirements)

Dangerous mark

Xn

Risk phrases

25-36/37/38-22-20/21/22

Safety phrases

26-45-37/39-36

Dangerous goods transport No.

UN 3335

WGK Germany

3

Hazard Note

 

RTECS

EK1610000

F

3-10-16-23

TSCA

Yes

Hazard Class

 

Packing Group

 

Upstream raw materials

 

Down stream product